How Often Should You Get NAD+? Common Protocols Explained

There Is No One Universal Protocol

NAD+ dosing varies significantly based on age, baseline health, goals, and the form being used (injection, IV, oral precursor). What works for an athlete optimizing recovery is very different from a protocol for general wellness maintenance.

Loading Phase vs Maintenance

Many providers begin with a more frequent loading phase — for example, multiple sessions over 1-2 weeks — before transitioning to maintenance. Maintenance frequency might range from twice monthly to quarterly.

Forms Matter

IV NAD+ infusions deliver the highest dose in one sitting but are most expensive. Subcutaneous injections are more accessible and can be self-administered with provider guidance. Topical NAD+ creams offer a slower, lower-dose option.

Not a One-Time Fix

NAD+ levels respond to many factors beyond supplementation — sleep, nutrition, exercise, and stress all matter. Discuss a protocol with a clinician who can integrate it into your broader wellness plan.