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Sexual Health

Sildenafil vs Tadalafil: Which Might Be Right for You?

Sildenafil and tadalafil are both FDA-approved treatments for erectile dysfunction. They work the same way but differ in important practical ways.

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Same Family, Different Profiles

Both sildenafil and tadalafil belong to a class of medications called PDE5 inhibitors. They work by improving blood flow, but they differ in onset time, duration of action, and side effect profile.

Onset and Duration

Sildenafil typically works within 30-60 minutes and lasts 4-6 hours. Tadalafil onsets in about an hour but can last up to 36 hours, which is why some patients prefer it for spontaneity.

Daily vs On-Demand Dosing

Tadalafil is available in low daily doses (2.5-5 mg) for patients who prefer continuous coverage. Sildenafil is generally taken on-demand before activity.

Choosing With a Provider

The right choice depends on your goals, lifestyle, other medications, and any underlying conditions. A licensed clinician can review your medical history and recommend an appropriate option. Both medications require a prescription.

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