Oral GLP
Compounded GLP-1 for convenient, needle-free weight management. Dissolves under the tongue for steady absorption—no injections required.
No commitment required • Free shipping

About This Treatment
GLP-1 oral offer a powerful, needle-free alternative to injections for weight management. Our compounded semaglutide lozenges dissolve slowly under the tongue, allowing for steady absorption through the oral mucosa—no needles, no hassle. Prepared by licensed US pharmacies, they provide an accessible and convenient option for those seeking effective support on their weight loss journey.
Semaglutide, the active ingredient in our GLP-1, has been extensively studied in clinical trials. Research has demonstrated significant weight loss results, with participants achieving an average weight loss of approximately 14–15% of body weight over one year when combined with diet and exercise. Individual results vary based on dosage, adherence, lifestyle habits, and overall health.
GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in your gut that helps regulate appetite and blood sugar. Semaglutide mimics this hormone, working to slow gastric emptying so you feel full longer, reduce hunger signals to your brain, and control cravings that can derail your weight loss efforts.
The oral format is designed for ease and convenience. This makes it an ideal choice for anyone who prefers a needle-free, on-the-go option without the complexity of injections or droppers.
Your treatment includes ongoing provider support and monitoring to help you achieve your goals safely. Our clinical team will work with you to find the right dosing protocol and provide guidance throughout your weight loss journey.
Got Questions?
Common Questions
Everything you need to know about this treatment
Still have questions?
Contact our care teamYour Journey
How RX Gleam works
Simple steps to your personalized treatment plan
Complete health profile
Answer questions about your health history, goals, and lifestyle. Takes about 5 minutes.
Provider review
A licensed physician reviews your information and determines if treatment is right for you.
Receive treatment
If approved, your medication ships directly to your door with ongoing support included.
Takes only 5 minutes • No commitment required
Patient Stories
Care you can count on
Real experiences from patients on their wellness journey
"The entire process was seamless from start to finish. I filled out my health profile, heard back from a provider the same day, and had my medication within a week. The ongoing support has been invaluable."
Verified Patient
California
"I was hesitant about telehealth at first, but the provider took the time to understand my health history before recommending anything. I feel confident knowing I have a medical team backing me up."
Verified Patient
Texas
"What sets RX Gleam apart is their communication. Every question I've had has been answered promptly and thoroughly. The patient portal makes it easy to stay connected with my care team."
Verified Patient
New York
Licensed US Providers
Free Discreet Shipping
HIPAA Compliant
US-Based Pharmacy
Take the next step
Ready to feel your best?
Complete a quick questionnaire to see if Oral GLP is right for you.
Takes only 5 minutes • No commitment required
Safety Information
Important details
Contains a boxed warning regarding thyroid C-cell tumors. Contraindicated in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Common side effects include nausea, diarrhea, decreased appetite, vomiting, and constipation—typically mild to moderate and diminish over time. Not recommended during pregnancy or breastfeeding. Discontinue at least 2 months before planned pregnancy. This is a compounded sublingual lozenge, not an FDA-approved product.
All prescriptions reviewed by licensed providers
We're here to help
Our care team is available to answer your questions