NAD+ Injection

NAD+ Injection: Important Safety Information

1. Introduction

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme present in every living cell, playing essential roles in energy metabolism, DNA repair, and cellular signaling. NAD+ injections are utilized for various wellness and anti-aging purposes. It is important to understand that compounded NAD+ injections have not been evaluated or approved by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality. For questions about NAD+ therapy, always consult a qualified healthcare professional.

2. Purpose & Potential Benefits

NAD+ may be administered to support cellular energy production, metabolic function, cognitive clarity, and overall wellness goals. Some individuals seek NAD+ therapy for its potential anti-aging and restorative properties. This information is provided for educational purposes only and does not constitute medical advice regarding specific indications, dosage, or treatment protocols.

3. Contraindications

You should NOT receive NAD+ injections if you:

• Have a known allergy or hypersensitivity to NAD+ or any components of the injection formulation

• Are pregnant, planning to become pregnant, or breastfeeding, unless specifically advised by your healthcare provider

• Have severe or unstable medical conditions such as uncontrolled diabetes, end-stage renal disease, significant heart disease, or liver dysfunction without first consulting your physician

• Have a history of serious allergic reactions (anaphylaxis) to injectable medications

4. Potential Risks & Side Effects

While many individuals tolerate NAD+ injections well, side effects can occur. Contact your healthcare provider immediately if any symptoms worsen or become unmanageable.

Injection Site Reactions:

• Redness, swelling, warmth, or pain at the injection site

• Bruising, minor bleeding, or temporary discoloration

• Localized itching or irritation

Gastrointestinal Effects:

• Nausea, vomiting, or loss of appetite

• Abdominal discomfort, cramping, or diarrhea

Neurological Effects:

• Headache or migraine, typically mild and transient

• Dizziness or lightheadedness, especially shortly after injection

• Flushing or warmth sensation

Energy & Mood Changes:

• Some individuals report temporary fatigue following treatment, with energy levels typically rebounding within 24 hours

• Jitteriness or restlessness, particularly if combined with caffeine or other stimulants

Allergic Reactions (Seek Emergency Care):

• Rash, hives, or severe itching

• Swelling of the face, lips, tongue, or throat

• Difficulty breathing, wheezing, or tightness in the chest

• If you suspect anaphylaxis, call 911 or seek emergency medical care immediately

5. Warnings & Precautions

Regulatory Status:

• Compounded NAD+ injections have not been evaluated by the FDA for safety, effectiveness, or quality

• If you prefer FDA-approved treatments, discuss alternative options with your healthcare provider

Medical Supervision:

• NAD+ injections should be administered under the guidance of a qualified healthcare professional

• Proper aseptic technique is critical to minimize risk of infection

• Always follow the administration instructions provided with your medication

Pre-Existing Conditions:

• Inform your healthcare provider of any heart, kidney, liver, or metabolic conditions

• Disclose all current medications, supplements, and herbal products

• Discuss any history of bleeding disorders or blood-thinning medication use

Special Populations:

• Safety and effectiveness in children and adolescents have not been established

• Pregnant or nursing women should consult their physician before use

• Elderly patients may require dose adjustments based on individual health status

6. Drug Interactions

• NAD+ may interact with certain prescription medications, over-the-counter drugs, herbal supplements, or dietary regimens

• Inform your healthcare provider about ALL medications and supplements you currently take before starting NAD+ therapy

• Be aware of potential changes in how other medications work, as NAD+ may theoretically affect various metabolic pathways

• Particular caution is advised if you take blood pressure medications, diabetes medications, or medications that affect the nervous system

7. Administration & Dosage

Method of Administration:

• NAD+ is typically administered via subcutaneous (SUBQ) injection into the fatty tissue beneath the skin

• Common injection sites include the abdomen, thigh, or upper arm

• Rotate injection sites to prevent tissue irritation or lipodystrophy

• Proper aseptic technique is essential to minimize infection risk

Dosage Guidelines:

• The appropriate dose varies based on individual factors including age, weight, health status, and treatment goals

• Follow the dosage and schedule exactly as prescribed by your healthcare provider

• Do NOT self-adjust dosage or discontinue treatment without consulting your provider

• Store medication as directed, typically refrigerated and protected from light

8. Reporting Adverse Events

• If you experience concerning side effects or a serious adverse event, seek immediate medical attention

• Contact your healthcare provider to report any unexpected reactions

• You may also report suspected adverse reactions to the FDA's MedWatch Program at 1-800-FDA-1088 or online at www.fda.gov/medwatch

9. Additional Precautions & Tips

• Hydration: Stay well-hydrated before and after treatment to help minimize potential side effects such as headaches or dizziness

• Timing: Many providers recommend morning injections to take advantage of potential energy-boosting effects during the day

• Lifestyle: A balanced diet, regular physical activity, and adequate sleep may help optimize the potential benefits of NAD+ therapy

• Follow-Up: Attend scheduled follow-up appointments and complete any recommended lab tests to monitor your response to treatment

• Storage: Keep your medication refrigerated as directed and check expiration dates before use

10. Disclaimer

These statements have not been evaluated by the Food and Drug Administration. NAD+ injections are not intended to diagnose, treat, cure, or prevent any disease. This document is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.

For questions or concerns about NAD+ injections, potential benefits, or side effects, please consult a qualified healthcare provider.